Old fathers seen to create global genetic disaster

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AN increasing trend of older fatherhood is potentially creating a global genetic disaster with devastating health consequences for offspring.

A major conference on human reproductive health in the Philippines will hear of mounting evidence that paternal aging is associated with a profound increase in sperm DNA damage that can burden offspring with mutational impacts, including schizophrenia, autism and childhood cancers.Speaking at the 2024 Congress of the Asia Pacific Initiative on Reproduction in Manila on May 26, Indian fertility specialist Dr.

'We know that sperm count, volume and motility decrease with age, but the focus should also be on genomic defects in sperm.'Patki, president of the Indian Society for Assisted Reproduction , said there had been major international studies on the impacts of maternal aging and reproductive health, but research and clinical trials on paternal aging were scant by comparison.

 

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