Factors potentially contributing to the decline of the mpox outbreak in the Netherlands, 2022 and 2023

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Research by experts from The Dutch National Institute for Public Health and the Environment (RIVM) hypothesize that it is not likely that preventive vaccination was a driver of the outbreak's decline, as the mpox incidence started to decline before the start of the vaccination program.

Factors potentially contributing to the decline of the mpox outbreak in the Netherlands, 2022 and 2023Research by experts from The Dutch National Institute for Public Health and the Environment hypothesize that it is not likely that preventive vaccination was a driver of the outbreak's decline, as the mpox incidence started to decline before the start of the vaccination program.

The overall vaccine uptake rate was 45.8%, with 35.4% of the target population being fully vaccinated. The efficacy of full vaccination in preventing symptomatic mpox was estimated at 68.2%, highlighting the effectiveness of vaccinations despite the outbreak's natural decline.Several key strategies for managing future mpox outbreaks are recommended.

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