Sponsored Content by Metrohm AGMay 20 2024Reviewed by Olivia Frost The medical field is a new frontier for Raman spectroscopy. Raman has already been employed in dentistry and cancer investigations, and it is now expanding into Point-of-Care applications.
A study group in Austria has recently demonstrated a successful distinction between healthy and diseased bone samples, as well as between two strains of staph bacteria, using a portable MIRA Raman spectrometer.1 Raman spectroscopy for cancer detection Raman’s molecular fingerprint spectra are sensitive enough to identify disease-related chemical changes. Surgeons can use compact Raman spectrometers to examine tumors during surgical procedures, allowing for quick decision-making. The sections below include application examples for breast and pancreatic cancer.
SERS amplifies the Raman signal without enhancing the competing fluorescence, making it more effective. Additionally, SERS enables the sensitive detection of analytes at concentrations as low as mg/L and, in some instances, down to µg/L. The peaks in SERS are sharp and well-defined, facilitating the efficient detection and identification of target analytes.
Figure 2. Detection of an antigen associated with pancreatic cancer is possible with surface-enhanced Raman spectroscopy . Image Credit: Metrohm AGFigure 3. MIRA XTR, a handheld Raman spectrometer from Metrohm. Image Credit: Metrohm AG Multiplex immunophenotyping of blood and breast cancer cells with Raman spectroscopy Another study used MIRA DS to evaluate a portable SERS-based ELISA for immunophenotyping of various types of red blood and breast cancer cell surfaces.5 Differentiating healthy and infected cells, as well as detecting multiple biotargets in a single sample, can aid in the informed treatment of various types of breast cancer.
Metrohm has reported a rather different SERS approach for the characterization of biological molecules.6 Conclusion Raman technology is increasingly utilized in innovative ways due to its numerous benefits, such as high sensitivity, capability for trace detection, compact size, and ability to deliver rapid results.
Health Health Latest News, Health Health Headlines
Similar News:You can also read news stories similar to this one that we have collected from other news sources.
Source: TheSun - 🏆 64. / 61 Read more »