Teprotumumab Treats Thyroid Eye Disease Across Age

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Thyroid Disease,Thyroid Dysfunction,Thyroid Associated Ophthalmopathy

Findings refute those of a prior study suggesting a better response in older vs younger patients.

TED is an autoimmune disease characterized by orbital inflammation and expansion of fat and muscles around the eyes, resulting in proptosis,In patients aged < 40 years, TED typically lacks restrictive myopathy, involves orbital fat expansion and proptosis with minimal to no periorbital inflammation or diplopia, and has low rates of dysthyroid optic neuropathy .

Asked to comment, session moderator Thanh D. Hoang, DO, director of the endocrinology division at the Uniformed Services University of the Health Sciences, Bethesda, Maryland, toldthat the data align with his experience using teprotumumab to treat TED."It works very well for a lot of my patients, some of them acute. But also some who have had it 10 or more years will also respond well to the medication.

 

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