The Tran lab in the Department of Molecular and Human Genetics is seeking a talented and motivated Postdoctoral Associate to lead projects that will examine the molecular mechanisms of neurodegeneration and axon regeneration in the central nervous system . : CNS neurons have a limited ability to recover from damage and for many neurodegenerative conditions there are limited treatment options.
Neuronal resilience to axonal damage- Our previous work demonstrated that retinal ganglion cells survival after nerve injury is strongly cell type dependent. This project will investigate cellular mechanisms underlying retinal ganglion cell resilience. In particular, we are interested in how features related to neural activity influence survival and axon regeneration after injury and in glaucoma.
Retinal ganglion cell type development- Retinal ganglion cells are remarkably diverse, comprising ~46 types in mice. We are using single cell multi-omic approaches to discover how retinal ganglion cell types are specified during development. BCM is centrally situated in Houston in the Texas Medical Center, the largest biomedical research center in the world, offering exceptional collaborative opportunities and resources.
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