Heightened risk of adverse neonatal outcomes from prenatal exposure to both cannabis and nicotine

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Nicotine,Prenatal,Embolism

A recent JAMA Network Open study found that combined prenatal use of nicotine and cannabis significantly increases risks for adverse perinatal outcomes, such as higher rates of hypertensive disease, preterm delivery, and elevated infant mortality compared to using neither or only one substance.

By Tarun Sai LomteMay 9 2024Reviewed by Susha Cheriyedath, M.Sc. In a recent study published in JAMA Network Open, researchers investigated the perinatal outcomes associated with the prenatal use of cannabis and nicotine products.

Study: Risk of Adverse Neonatal Outcomes After Combined Prenatal Cannabis and Nicotine Exposure. Image Credit: ibragimova / Shutterstock Patients were classified as having severe maternal morbidity if they had aneurysm, myocardial infarction, acute kidney failure, amniotic fluid embolism, acute respiratory distress syndrome, eclampsia, ventricular fibrillation, cardiac arrest, severe anesthesia complications, heart failure, hysterectomy, air and thrombotic embolism, pulmonary edema, puerperal cerebrovascular disorders, or disseminated intravascular coagulation.

Related StoriesMeanwhile, the prevalence of combined use was stable. Dual users were more likely to be White, self-insured, and have < five prenatal visits during pregnancy than controls. Moreover, the proportion of chronic hypertension, diabetes, and mental health disorders was higher among those using both nicotine and cannabis compared to controls.

 

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