Ketamine shows complex neural patterns, affecting inhibitory and excitatory brain circuits.led by Flora Moujaes at Yale University investigates ketamine's effects on brain activity and behavior in healthy individuals, revealing complexpatterns. Understanding these nuances could lead to more targeted treatments for depression, offering hope for those who have not responded to conventional
Ketamine was developed in the 1960s to be used as a battlefield anesthetic in the Vietnam War as well as in health care settings. It was historically used in highly regulated and supervised health care facilities but its usage has changed significantly since then.Ketamine is approved by the United States Food and Drug Administration as an anesthetic and is widely used for short, painful procedures that require immobilization.
This may be due to the influence it has between different parts of the brain; for example, the connection between two excitatory parts of the brain or between an excitatory part and an inhibitory part. It may also target specific types of cells in the brain more strongly based on their receptor makeup. Or it could be affecting various smaller circuits within the brain.
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