Researchers found that Black Americans who experience racism in their 40s and 50s are more likely to have increased serum levels of AD biomarkers p-tau181 and neurofilament light more than a decade later.
Blood samples were tested for serum phosphorylated tau181 , a marker of AD pathology; NfL, a nonspecific marker of neurodegeneration; and glial fibrillary acidic protein , a marker of brain inflammation. Investigators speculated based on previous research that the stress related to discrimination may be associated with reductions in hippocampal and prefrontal cortex volumes and neurodegeneration in general.
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