Exploring the potential of ketogenic diets in managing epilepsy

By Pooja Toshniwal PahariaApr 26 2024Reviewed by Lily Ramsey, LLM In a recent review published in Nutrients, researchers investigated the mechanisms of action, efficacy, and side effects of ketogenic diet variations in epileptic patients.Background Epilepsy is a neurological illness that has harmful effects on the central nervous system, hepatotoxicity, and teratogenicity.

Ketogenic diet variants, recommendations, mechanisms, and adverse effects KD is a high-fat, low-carbohydrate, and low to adequate protein diet that results in ketone bodies. It contains a 4:1 weight ratio of lipids to nonlipids, with fat accounting for 80% of total calories, proteins for 15%, and carbohydrates for 5.0%.

They also restore the gut microbiota, activate adenosine triphosphate -sensitive potassium currents, boost mitochondrial oxidative phosphorylation, improve antioxidant production, and inhibit the mammalian target of the rapamycin pathway. KDs also balance the brain's excitatory and inhibitory neurotransmitter systems.

Research on ketogenic diet efficacy in epileptic patients Randomized clinical trials have compared the effectiveness of standard antiepileptic medication to the MAD in treating intractable seizures in children. Randomized controlled trials demonstrated that patients who reached seizure-free status on the ketogenic diet may remain on it even if they experienced breakthrough seizures.

Health Health Latest News, Health Health Headlines

Similar News:You can also read news stories similar to this one that we have collected from other news sources.

Exploring ferroptosis and its implications in lung cancerAn estimated 2.2 million people suffer from lung cancer worldwide, making it the second most common type of cancer. Though improvements in treatment have been made, the overall survival rate of lung cancer patients is low, and it remains a leading cause of death, accounting for 18% of total cancer-related deaths in 2022.
Source: medical_xpress - 🏆 101. / 51 Read more »

Exploring ferumoxytol: A new frontier in MRI contrast agentsMagnetic resonance imaging (MRI) is a cornerstone in the landscape of medical diagnostics, celebrated for its non-ionizing and non-invasive nature. With nearly 40% of MRI procedures requiring contrast agents for optimal sensitivity, the quest for safer and more effective alternatives to gadolinium-based agents (GBCAs) has intensified.
Source: medical_xpress - 🏆 101. / 51 Read more »