Researchers create first artificial, modifiable cells with programmable DNA

Researchers at University of North Carolina-Chapel Hill have successfully engineered functional artificial cells in the lab which behave like living cells.

“With this discovery, we can think of engineering fabrics or tissues that can be sensitive to changes in their environment and behave in dynamic ways,” states Freeman.Cells and tissues rely on proteins to carry out various tasks and construct vital structures. One such structure, the cytoskeleton, serves as the framework of a cell, enabling it to function properly.

This method orchestrates a collaboration between peptides, the basic building blocks of proteins, and repurposed genetic material to construct a cytoskeleton. While synthetic cells crafted by the Freeman Lab lack the complexity of living cells, they offer a level of predictability and resilience to harsh conditions such as extreme temperatures.

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