New tool hunts for Alzheimer's clues in gut microbiome

Apr 23 2024Cleveland Clinic Cleveland Clinic researchers are using artificial intelligence to uncover the link between the gut microbiome and Alzheimer's disease.

Bacteria release metabolites into our systems as they break down the food we eat for energy. The metabolites then interact with and influence cells, fueling cellular processes that can be helpful or detrimental to health. In addition to Alzheimer's disease, researchers have connected metabolites to heart disease, infertility, cancers and autoimmune disorders and allergies.

Study first author and Cheng Lab postdoctoral fellow Yunguang Qiu, PhD spearheaded a team that included J. Mark Brown, PhD, Director of Research, CMMH; James Leverenz, MD, Director of Cleveland Clinic Luo Ruvo Center for Brain Health and Director of the Cleveland Alzheimer's Disease Research Center; and neuropsychologist Jessica Caldwell, PhD, ABPP/CN. Director of the Women's Alzheimer's Movement Prevention Center at Cleveland Clinic Nevada.

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