Large-scale study identifies new approach to early Alzheimer's detection

Apr 23 2024University of Gothenburg Digital memory test and a blood sample - this combination will be tested for its potential to identify early Alzheimer's disease in a new research study. Over a hundred healthcare centers are part of the study that is now inviting participants to sign up. At least 3,000, preferably many more participants are needed for the study to be successful.

Tests of memory and thinking ability at home Starting point is a digital study portal, available in Swedish, English, Finnish and Arabic, where participants receive all information about the study and clear instructions about the next steps. First, cognition, i.e. memory and thinking ability, is tested at home using digital tools for three months. Participants are then invited to provide a blood sample at any of the 111 sampling points around VGR.

Signs of Alzheimer's in a simple blood test Central hub of the study is the internationally renowned research and laboratory environment in neurochemistry, located at the Sahlgrenska Academy at the University of Gothenburg and the Sahlgrenska University Hospital Mölndal, with professors Kaj Blennow and Henrik Zetterberg at the helm.

The need for earlier diagnosis is widely accepted, also in view of the new treatments that are around the corner. Many if not most diagnoses are made in primary care in Sweden, so diagnostics must be strengthened there, and knowledge is needed about whether it will be feasible to screen for Alzheimer's in the general population. In the short term, society does not have the resources to establish a lot of new specialized memory clinics.

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