Has Immunotherapy Found Its Place in Pancreatic Cancer?

  • 📰 Medscape
  • ⏱ Reading Time:
  • 30 sec. here
  • 27 min. at publisher
  • 📊 Quality Score:
  • News: 102%
  • Publisher: 55%

Malignant Pancreatic Neoplasm News

Pancreatic Cancer,Cancer Of The Pancreas,Biologic Therapy

A new study suggested that adding nivolumab to neoadjuvant treatment improves outcomes in patients with borderline resectable pancreatic cancer.

The trials, however, have focused on adding immune checkpoint inhibitors to chemotherapy in metastatic disease, leaving open the question of whether immunotherapy might have a role in the neoadjuvant setting before surgery.included 28 patients with borderline resectable pancreatic cancer, meaning that tumors had some degree of vascular involvement. About 20% of pancreatic tumors are borderline resectable, Wainberg said.

Among patients receiving surgery, 21 had R0 resections, meaning negative surgical margins with no tumor left behind. This is key because R0 resections predict longer survival, and"every effort should be made to achieve" this outcome, Wainberg said. The remaining patient had an R1 resection. The study outcomes, especially among the surgery cohort, stand in contrast to those observed in patients who receive the current standard neoadjuvant regimen for borderline resectable pancreatic cancer, mFOLFIRINOX alone, with studies finding a median overall survival of

 

Thank you for your comment. Your comment will be published after being reviewed.
Please try again later.
We have summarized this news so that you can read it quickly. If you are interested in the news, you can read the full text here. Read more:

 /  🏆 386. in HEALTH

Health Health Latest News, Health Health Headlines

Similar News:You can also read news stories similar to this one that we have collected from other news sources.

Immunotherapy for Alzheimer's disease shows promise in mouse studyScientists have shown that treating mice with an antibody that blocks the interaction between APOE proteins (white) sprinkled within Alzheimer's disease plaques and the LILRB4 receptor on microglia cells (purple) activates them to clean up damaging plaques (blue) in the brain.
Source: ScienceDaily - 🏆 452. / 53 Read more »

New immunotherapy could make blood more 'youthful,' mouse study hintsEmily is a health news writer based in London, United Kingdom. She holds a bachelor's degree in biology from Durham University and a master's degree in clinical and therapeutic neuroscience from Oxford University. She has worked in science communication, medical writing and as a local news reporter while undertaking journalism training.
Source: LiveScience - 🏆 538. / 51 Read more »

Adding Vaccine to Immunotherapy for Liver Cancer Shows Promise in Early TrialA custom-made anti-tumor vaccine added to standard immunotherapy was twice as likely to shrink liver cancer as when a patient received immunotherapy alone, a new study shows.
Source: MedicineNet - 🏆 575. / 51 Read more »

Subcutaneous Immunotherapy: Better Life for Patients With CancerAdministering immunotherapy via subcutaneous infections could save clinicians time and money and patients may prefer it.
Source: Medscape - 🏆 386. / 55 Read more »