Family colon cancer risk similar for siblings and half siblings

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(Reuters Health) - - Siblings of people with colorectal cancer are themselves at higher risk for the disease - but a new study suggests ...

- - Siblings of people with colorectal cancer are themselves at higher risk for the disease - but a new study suggests half-siblings face nearly as a high a risk.

Half-siblings of colorectal cancer patients had a 6 percent cumulative lifetime risk, which is 1.5 times the risk without a family history. An estimated 70 to 80 percent of the risk of these tumors depends on the level of poverty or affluence where people live, as well as other environmental factors like social and cultural traditions and lifestyle, researchers note. About 2 to 5 percent of risk depends on genetics, but the remaining causes of inherited colorectal cancers are unknown.

There wasn't a meaningful increase in the risk of colorectal cancer when people had only one second-degree relative other than a half sibling develop these tumors, however.

 

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