Longest Covid infection lasted nearly two years as scientists warn of mutations

The longest lasting Covid infection recorded was recorded at nearly two years, scientists have revealed.

It is believed the initial emergence of the Omicron variant of Covid in late 2021 originated in an immunocompromised person, highlighting the importance of keeping a close eye on such patients. The elderly man had received multiple Covid vaccinations without any measurable antibody response upon being admitted to hospital.

The prolonged infection led to the emergence of a novel, immune-evasive variant of the virus due to its extensive evolution within a host. "This case underscores the risk of persistent SARS-CoV-2 infections in immunocompromised individuals as unique SARS-CoV-2 viral variants may emerge due to extensive intra-host evolution," Dr Vergouwe explained.

This could then be combined with genomic surveillance of the virus to assess the public health threat together with public health professionals.

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Longest ever case of Covid lasted 613 DAYS and turned into ultra-mutated variant: Immunocompromised...The patient was admitted to Amsterdam University Medical Centre in February 2022 with the omicron variant of Covid.
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