Your Good Health: Low iron levels might affect blood donor’s depression

Dear Dr. Roach: I am wondering if there is any link between low iron and depression/anxiety. I am a 37-year-old woman, and I started taking Lexapro a few years ago. I upped my dose last year because I wasn’t feeling great, and my doctor and I decided that it was a good step.

I haven’t donated in about five months, and I am feeling much better regarding my depression. I know that donating blood affects iron levels, but does it also affect the concentration of Lexapro in my body? If not, can low iron be contributing to my depression? I would love to know the answer so that I can possibly continue to donate, perhaps less frequently.First off, thank you for donating so regularly.

However, there are many reasons, both inside and outside of your body, that can make depressive symptoms worse. Still, if you do have low iron levels, you can replace iron faster with an iron supplement. If your depression then gets better, this would be pretty good evidence that the low iron does affect your mood.

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