Tocilizumab Withdrawal Post Remission in Still's Disease

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Biologic Therapy News

Biologics,Remission,Juvenile Rheumatoid Arthritis

Longer tocilizumab administration intervals and lower prednisolone doses seemed pivotal for successful tocilizumab withdrawal while maintaining remission in patients with AOSD.

administration results in high remission rates in adult-onset Still's disease , but the recurrence rate increases on tocilizumab discontinuation, with a longer tocilizumab interval and lowerTocilizumab is effective in reducing systemic inflammation and lowering glucocorticoid doses in patients with AOSD; however, the possibility of tocilizumab withdrawal has not been explored.

The systemic feature score, Pouchot score, and modified Pouchot score were used to evaluate the disease activity.

 

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