Infant Microbiome Development Minimally Affected by Diet, but Metabolite Profiles Differ

Diet has only a marginal impact on microbiome development in infancy, although metabolite profiles differ between breast- and formula-fed infants; circadian rhythm of the gut microbiome is detectable as early as 2 weeks after birth.

They also made note of the time of day that the stool sample was collected to assess 24-hour oscillations of the microbiome in relation to dietary exposure.Global microbiota assembly of infants is primarily affected by age and less so by diet. All infants showed a gradual increase in gut microbe diversity, and at 24 months, there was no observable difference between the groups.

GOS-supplemented formula was more effective at promoting sustained levels of bifidobacteria than formula containing bifidobacteria.

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