Why blood pressure drug spironolactone is being used for acne

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Marina Kopf is an associate producer with the NBC News Health and Medical Unit.

Acne didn’t take hold of JJ Boparai’s skin until she was in her late 20s. “I’d never had acne like this, my face was just covered,” said the 31-year-old from Metuchen, New Jersey, adding that experiencing acne as an adult was “horrible psychologically.” Boparai’s breakouts — which she described as “very cystic, like a lot of under the skin, big, painful, ones, a lot on my chin and cheeks” — were stubborn.

“If we could use more spironolactone, that might help us use less antibiotics,” said Barbieri, who also co-chairs the group’s acne guidelines work group. “That’s going to create less antibiotic resistance in the community, and less antibiotic-associated complications for patients, like disrupting the microbiome.” Is spironolactone safe for acne treatment? Spironolactone isn’t approved by the Food and Drug Administration for acne and is prescribed off-label.

 

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