Long Covid leaves traces in the blood that could lead to successful treatment, study suggests

leaves telltale signs in the blood which could pave the way for targeted treatment, new research suggests.

In an analysis of more than 650 people who had been in hospital with severe Covid-19, patients with prolonged symptoms showed evidence of their immune system being activated.How this activation happened depended on the type of symptoms they mainly had, for example fatigue or brain fog. He said the study contains a "hopeful message which says that there are these biological pathways that are activated from different forms of persistent symptomatology after Covid, and people aren’t imagining it.“A lot of the symptoms do ultimately resolve and we’re continuing this study and looking at later time points.”

Researchers found that, compared to patients who had fully recovered, those with long Covid showed a pattern of immune system activation indicating inflammation of myeloid cells and activation of a family of immune system proteins called the complement system.

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