Apr 5 2024University of California - Los Angeles Health Sciences Findings A pilot study led by UCLA Health Jonsson Comprehensive Cancer Center investigators suggests that for people with borderline resectable pancreatic cancer, administrating an immunotherapy drug in combination with chemotherapy before surgery is safe and may improve long-term outcomes.
Dr. Zev Wainberg, co-director of the UCLA Health GI Oncology Program and first author of the study abstract Method The study included 28 patients with borderline resectable pancreatic cancer. Twenty-six of the participants completed at least three cycles of the combination therapy and 24 underwent surgery. Genetic sequencing was performed on 21 post-treatment resected tumors, six patient-matched diagnostic pre-treatment biopsies, and nine resected tumors from non-trial patients treated with chemotherapy alone.
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