Researchers turn back the clock on cancer cells to offer new treatment paradigm

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Scientists reversed an aggressive cancer, reverting malignant cells towards a more normal state. Rhabdoid tumors are an aggressive cancer which is missing a key tumor suppressor protein. Scientists discovered that removing a second protein from cancer cells already experiencing tumor suppressor loss can reverse cancer cell identity.

Researchers turn back the clock on cancer cells to offer new treatment paradigm." ScienceDaily. ScienceDaily, 27 March 2024. <www.sciencedaily.comSt. Jude Children's Research Hospital. . Researchers turn back the clock on cancer cells to offer new treatment paradigm.

Mutations of the tumor suppressor p53 not only have a growth-promoting effect on the cancer cells themselves, but also influence the cells in the tumor's microenvironment. Scientists have now ... Scientists have shown it is possible to reverse a key process that allows pancreatic cancer cells to grow and spread around the body. These findings show that a protein called GREM1 is key to ...

Scientists have discovered stem cells of the hematopoietic system in glioblastomas, the most aggressive form of brain tumor. These hematopoietic stem cells promote division of the cancer cells and at ... Viruses churn out genetic material in parts of the cell where it's not supposed to be. Cancer cells do too. A new study shows that a tumor-suppressor enzyme called DAPK3 is an essential ...

 

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