How COVID-19 Treatments Affect Patients With IBD

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Inflammatory bowel disease therapies for patients may need to be briefly halted during treatment for COVID-19, but it does not increase flares.

therapies for patients may need to be briefly halted during treatment for COVID-19, but it does not escalate IBD flares, with prior vaccination for COVID-19 helping reduce complications from the virus.Patients with IBD who receive immunosuppressive agents are at an increased risk of developing severe SARS-CoV-2 infection; however, the effects of COVID-19 vaccination and treatment on the outcomes in patients with IBD are less known.

Researchers assessed the effect of COVID-19 medications in 127 patients with IBD who were diagnosed with COVID-19 after the advent of vaccines and release of antiviral therapies. Patients were stratified into those who received treatment for COVID-19 , defined as the use of antivirals and/or intravenous antibodies, and those who did not receive treatment for COVID-19 .The secondary outcomes were the percentage of patients who had their IBD therapy withheld and rates of IBD flare post COVID-19.After adjusting for multiple factors, the likelihood of withholding IBD treatment was higher in patients being treated for COVID-19 (aOR, 6.

 

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