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Predicting immunotherapy response and guiding combination therapy with MOTIF

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Tumor mutation burden (TMB) is considered an important predictive biomarker for the efficacy of immunotherapy. However, in cancer types where TMB is not positively correlated with the abundance of CD8+ T cells, TMB cannot predict the efficacy of immunotherapy.

Predicting immunotherapy response and guiding combination therapy with MOTIF retrieved 19 March 2024 from https://medicalxpress.com/news/2024-03-immunotherapy-response-combination-therapy-motif.html

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