Scientists unravel mystery of drug response in small cell lung cancer

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Small cell lung cancer (SCLC) is a highly aggressive tumor of the lung that occurs especially in heavy smokers. Due to the rapid spread of this tumor type, most patients can only be treated with chemotherapy with remarkable initial anti-tumor efficacy. However, relapse often occurs over the course of time.

Scientists unravel mystery of drug response in small cell lung cancer retrieved 13 March 2024 from https://medicalxpress.com/news/2024-03-scientists-unravel-mystery-drug-response.html

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University of Cologne Identifies Mechanisms Governing Relapse in Small Cell Lung CancerA research team at the University of Cologne has identified the mechanisms governing relapse in small cell lung cancer (SCLC) for the first time. Therapy is typically efficacious at the beginning due to treatment-sensitive cancer cells, but other numerous and very different cancer cells are hidden within these populations.
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