By Dr. Chinta SidharthanMar 13 2024Reviewed by Lily Ramsey, LLM In a recent study published in Nature's Signal Transduction and Targeted Therapy, scientists reviewed the therapeutic potential of and molecular mechanisms through which dietary interventions impact a wide range of human diseases, such as cardiovascular disease, autoimmune, neurodegenerative, and metabolic diseases, as well as cancer.
Results from various epidemiological studies have found that specific dietary patterns modulate the risk of various diseases, including cancer. The immunosuppressive environment inside tumors is a result of the cancer cells depriving the immune cells of essential metabolites such as oxygen and glucose while increasing the levels of adenosine, lactase, and other mediators that further decrease immune cell function.
Dietary interventions and cancer The impact of dietary interventions on diseases, including cancer, can be deciphered better with a thorough understanding of the metabolic pathways of macronutrients such as proteins, fats, and carbohydrates. The researchers also reviewed studies that evaluated the role of dietary factors in cancer treatment, especially the use of nutritional interventions to improve the efficacy of immunotherapy and other cancer treatments.
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