Matthew Perry Cause of Death, 'Acute Effects of Ketamine'

died from"the acute effects of ketamine," a drug that is used to treat depression and is also used as a recreational drug.

The Los Angeles County Medical Examiner's Office just released the toxicology report, concluding Perry had taken ketamine infusion therapy for depression and anxiety a week-and-a-half before his death. The ketamine in his system at the time of his death, however,"could not be from that infusion therapy, since ketamine's half-life is 3 to 4 hours, or less."

According to the Medical Examiner, the ketamine in Perry's system caused both cardiovascular overstimulation and respiratory depression.The contributory factors in Perry's death included drowning, coronary artery disease, and buprenorphine effects. Buprenorphine is used to ween addicts off opioids.What's interesting ... according to the M.E.

Although smoking was not listed as a contributing factor in Perry's death, the report notes he smoked 2 packs of cigarettes a day, had COPD/emphysema and diabetes.TMZ broke the story ... on Oct. 28,in his jacuzzi after playing 2 hours of pickleball at Riviera Country Club near his home in Pacific Palisades. First responders rushed to the property on a cardiac arrest call, and he was declared deceased on the scene after an apparent drowning.Play video contentLike we told you ...

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