What a Trip: Mental Health’s Psychedelic Revolution

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ADDitude examines the promise, and perils, of psychedelic-assisted therapy in the first of a two-part series exploring and explaining how ketamine, MDMA, and psilocybin are used with therapy for mental health care.

Ecstasy. ‘Shrooms. Special K. These illicit drugs, once relegated to nightclubs and music festivals, have once again become revolutionary medicines with thrilling potential to help people suffering from mental health conditions, including depression, post-traumatic stress disorder , opioid and alcohol addiction, eating disorders, and more.that is legal nationwide — has exploded.

In 2000, a new era of research began when scientists from Johns Hopkins University secured regulatory approval to study the effect of psychedelics on behavior, brain function, learning and memory, and mood. In 2020, Johns Hopkins opened a psychedelics research center. Since then, most of the country’s elite universities have followed suit.

In clinical trials and at carefully selected doses, ecstasy, ketamine, and psilocybin have produced generally mild side effects. When taken at higher doses, these drugs can cause disorientation, paranoia, and panic, which can lead to dangerous behavior, accidents, self-harm, and even suicidality. Other adverse effects include the potential for hallucinogen persisting perception disorder , misuse, and abuse.

 

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