Researchers transplant stem cells into brain to reverse stroke and degenerative diseases

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Stem Cells,Brain,Stroke

Local researchers have successfully transplanted stem cells into the brain to reverse the effects of stroke and degenerative diseases such as Parkinson’s and Alzheimer’s. The study conducted by scientists from Duke-NUS Medical School showed promising results in mice with induced ischaemic strokes. Within a month of the transplant, the mice regained normal movement. Stroke is the fourth-leading cause of death in Singapore.

In a major breakthrough, local researchers have transplanted stem cells into the brain to reverse the ravages of stroke and degenerative diseases such as Parkinson’s and Alzheimer’s. The scientists from the Duke-NUS Medical School (Duke-NUS) GK Goh Centre for Neuroscience grew neurons, or nerve cells, from immature stem cells and used them to repair the brains in mice which had ischaemic strokes induced.

Within a month of the transplant, the mice were moving about normally, in contrast to when they had the strokes. Ischaemic stroke occurs when a blood clot blocks or plugs an artery leading to the brain, cutting off blood supply and killing brain cells. It can have serious, even life-threatening, consequences. According to the Ministry of Health, stroke is the fourth-leading cause of death in Singapore, with a prevalence of 4 per cent among adults aged 50 and above

 

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