How monkey's testicles are being used to help young boys with cancer

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These monkeys could bring a whole lot of joy to the world

Grady at 11 months old – One in three children are left infertile from chemotherapy or radiation that helped save their lives Boys are born with stem cells inside little tubes in the testes, cells that start producing sperm after puberty’s testosterone jolt.

Colleagues at the Oregon National Primate Research Center injected some of that sperm into eggs from female monkeys and implanted the resulting embryos. Girls’ eggs are in an immature state before puberty. Researchers have removed and frozen strips of ovarian tissue harbouring egg follicles from young women before cancer treatment, in hopes that when transplanted back later the immature eggs would resume development.

Surgery involving the boys’ testicular tissue is less invasive, noted Orwig, who also is researching ways to reinsert sperm-producing stem cells where they belong rather than the more roundabout technique.

 

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