Mind-altering ketamine becomes latest pain treatment, despite little research or regulation

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Several people report that the drug saved their lives. A clinic in Winston-Salem said it offers the treatment.

Some experts worry the U.S. may be repeating the mistakes that led to the opioid crisis by overprescribing an unproven drug with safety and abuse risks.Prescriptions for ketamine have soared in recent years, driven by for-profit clinics and telehealth services offering the medication as a treatment for pain, depression, anxiety and other conditions. The generic drug can be purchased cheaply and prescribed by most physicians and some nurses, regardless of their training.

Daniel Bass, of Southgate, Kentucky, found the visual disturbances “horrifying.” His doctors prescribed four- to six-hour IV infusions of ketamine for pain related to a rare bone and joint disorder. Seated in a bare hospital room with no stimulation or guidance on the drug's psychological effects, Bass says he felt"like a lab rat.”

“We want patients to disassociate or feel separate from their pain, depression or anxiety,” said Dr. David Mahjoubi, owner of Ketamine Healing Clinic in Los Angeles. “If they feel like they’re just sitting in the chair the whole time, we actually give them more.” Sending ketamine through the mail has become its own profitable business for telehealth services, such as MindBloom, which jumped into the space after regulators relaxed online prescribing rules during COVID-19.“The literature for the nasal and oral formulations is pretty scant,” said Dr. Eric Schwenk of Thomas Jefferson University. “There’s just not a lot of good evidence to guide you.”

The recent boom has been fueled, in part, by venture capital investors. Another set of consulting businesses offer to help doctors set up new clinics.

 

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Mind-altering ketamine becomes latest pain treatment, despite little research or regulationSeveral people report that the drug saved their lives. A clinic in Winston-Salem said it offers the treatment.
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