Targeted drug may offer a new treatment option for patients with relapsed blood cancer

Reviewed by Lily Ramsey, LLMNov 6 2023 Solove Research Institute , may offer a new treatment option for patients with blood cancers, including chronic lymphocytic leukemia and Non-Hodgkin lymphoma whose disease has stopped responding to standard treatments.

"Blood cancers that have relapsed after initial treatments can be difficult to treat, and even with our effective medications, some patients run out of standard treatment options. In this trial, nemtabrutinib looks very promising for patients whose cancer has progressive after other treatments." said Woyach, who is co-leader of the Leukemia Research Program at the OSUCCC – James.

Study methods and results The researchers tested the new drug on 47 patients who have had at least two prior therapies for their blood cancer. Over half of these patients had relapsed CLL, while the others had NHL. The researchers gave these patients one pill of nemtabrutinib every day, with different doses along the trial. They observed the patients' response to the drug over time and monitored them for side effects.

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