A registry study covering all Finnish and Swedish children and their family members identified 16 major risk factors for a severe RSV infection. The researchers created a clinical prediction model to predict the risk of hospitalisation from an RSV infection and showed that the model performed well in both countries.
In recent years, both a long-acting antibody that protects against an RSV infection and a vaccine given to mothers during pregnancy have been developed to prevent RSV infections. When targeted properly, such drugs can prevent a large number of complications in young children and decrease the number of hospital and intensive care stays, but it is not yet clear how widely these approaches should be used.
RSV causes severe infections, especially in children under one year of age. In Finland, it is one of the most common causes of hospitalisation of young children and a major cause of infant mortality worldwide." In Finland, one in three children under one year of age is infected with RSV, and around 1000 of these children require hospital treatment for the RSV infection, significantly more than for influenza or coronavirus.
Related StoriesFor creating the prediction model, health data were harmonised and coded for AI use as part of the Finnish FinRegistry study. The resulting model was replicated in the corresponding Swedish registry data.
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