Oct 24 2023 6 million award from the National Institutes of Health will allow neurosurgical, neurology and neuroscience researchers at The Ohio State University Wexner Medical Center and College of Medicine to test a novel diagnosis and treatment combination for painful diabetic neuropathy. The approach combines spinal cord stimulation with measurement of small fiber nerve activity using a patent-pending device called Detecting Early Neuropathy .
Options to diagnose and treat peripheral neuropathy are very limited and ineffective, and thus more research is needed to develop and test new options that can reduce the pain, discomfort, high medical costs and loss of productivity for patients. Patients have very few options for treatment of their debilitating peripheral neuropathy, and there's an over-reliance on addictive opioid pain medications which are only partially effective.
It is estimated that up to 70% of patients with diabetes will develop neuropathy, some even in the pre-diabetes state. Other small fiber neuropathies are caused by chemotherapy, aging, and now - long COVID, said Townsend, whose research program investigates nervous system plasticity, remodeling, and regeneration in situations of metabolic disease, such as obesity, diabetes, aging, cardiometabolic disease, and peripheral neuropathy.
Together, this research collaboration allows synergistic clinical and translational data collection to investigate clinical outcomes and cellular mechanisms underlying the therapeutic effects of SCS for patients with painful diabetic neuropathy.
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