Can Beta-carotene boost cognitive health? Study reveals promising insights

By Dr. Priyom Bose, Ph.D.Oct 22 2023Reviewed by Benedette Cuffari, M.Sc. In a recent study published in the journal Brain Sciences, scientists examine the role of β-carotene in maintaining cognitive performance and mental health, either alone or in combination with other dietary components.

The current study included all adult participants without mental disorders. Several types of studies were considered for the analysis, including randomized clinical trials, prospective or cross-sectional studies, and longitudinal studies. Importantly, cognitive function is not stable, as it continually evolves throughout life. Aging is associated with cognitive impairment, with one recent study estimating that 19% of individuals under 75 years of age suffer from variable degrees of cognitive dysfunction compared to about 29% among people above 85 years of age.

Use of β-carotene to combat cognitive dysfunction in adults Carotenoids are common antioxidants and anti-inflammatory agents that can effectively improve cognitive health. To date, there are no guidelines or recommendations regarding the optimal dose of carotenoid intake for favorable outcomes. One recent study indicated that β-carotene dietary intake was inversely associated with cognitive function decline. A linear dose-response relationship between dietary β-carotene intake and Consortium to Establish a Registry for Alzheimer's Disease word learning test, alpha-fetoprotein test, and Defense Subject Standardized Test results were observed; however, these results varied based on sex.

Many randomized clinical trials have supported the protective role of β-carotene against cognitive impairment. For example, the Physicians' Health Study recommended that 50 mg of β-carotene on every alternate day could improve verbal and cognitive memory in adults.

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