Beyond the gut: Crohn's disease's oral clues for timely diagnosis

By Dr. Priyom Bose, Ph.D.Oct 12 2023Reviewed by Lily Ramsey, LLM Crohn's disease , a form of inflammatory bowel disease , is marked by chronic inflammation throughout the gastrointestinal tract.

Insights into CD CD predominantly impacts the lower gastrointestinal tract, particularly the ileocolonic region. It's a chronic condition characterized by periods of remission and exacerbation, affecting both men and women equally. CD exhibits a bimodal incidence, with the first peak between ages 20 and 40 and the second between 50 and 60.

Environmental factors Studies have linked CD to specific toothpaste choices and a history of appendectomy. In contrast, breastfeeding and childhood contact with animals appear to offer protective factors against CD development. Oral manifestations Oral symptoms can serve as the first signs of CD, affecting roughly 9% of adults and a striking 80% of children with the condition. Lesions are commonly found on the lower lips and gums and, less frequently, in the fauces' tongue, soft palate, uvula, and pillars.

Non-specific manifestations involve oral erythema nodosum, multiple neutrophilic dermatoses, and aphthous ulcers.

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