“We need to know more about the optimal strategies to reduce kidney disease risk in adults with obesity,” said study author Meera Harhay, MD, the medical director of clinical research at Drexel University in Philadelphia.for kidney disease, a leading cause of death in the United States. Hormonal changes related to extra body fat can increase body fluid volume, raise blood pressure, and promote insulin resistance.
They found that for every 11 pounds people gained, their risk of kidney disease shot up by 34%. But losing weight did not decrease the risk. This suggests that preventing weight gain may be more important than weight loss. Once scar tissue forms in the kidneys, that damage can’t be undone. But regular exercise may help the body survive that damage, the researchers surmised.
“For about 2 decades now, there has been in-depth research into what is the stronger factor for our longevity and disease risk,” said Matthew Ahmadi, PhD, a postdoctoral researcher at the University of Sydney, in Australia. “Is ‘fitness’ the primary driver, ‘fatness,’ or a balanced combination between the two?”co-authored by Ahmadi, people who walked at a faster pace had a 36% lower risk of dying during the study period than those who walked more slowly.
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