walls and transport vesicles that carry them across these walls. The researchers showed that nanoparticles will re-enter the bloodstream following lymphatic drainage, and hypothesized that these nanoparticles will eventually return to the tumor for another opportunity to treat it.
Nguyen noted that the field of nanomedicine has evolved since the publication of the nanoparticle entry study in 2020."We got more pushback from other researchers on that study compared to this one," he said."People have started to accept that the EPR effect is flawed.", future research could address this issue through nanoparticle treatments that prevent lymphatic drainage.
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