A drug invented in Melbourne to treat a lethal bone marrow cancer is set to become a billion-dollar global blockbuster after US regulators on FridayMomelotinib was invented by an Australian team in Burnley in the late 1990s, and the drug was purchased by pharma giant GSK in 2022 for
“There are few stories that really encapsulate how great Australian science can be better than this one,” said Professor Mark Dawson, co-head of the Cancer Biology and Therapeutics Program at the Peter MacCallum Cancer Centre. He was not involved in the drug’s development. In the early 2000s, researchers around the world linked genetic dysfunction in the newly discovered kinases to a pair of diseases in which the proteins go rogue, pumping out far too many blood cells.
“One of the doctors said ‘your blood is like jam, it’s very thick’,” said Young, who is a committee member of advocacy group MPN Alliance Australia.
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