Q&A: Expert discusses the damage E. coli can have on the body and the treatment options available to patients

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E. coli is a well-known risk factor in food preparation and hygiene, but how does it cause damage in the body and how does an outbreak have the power to send hundreds to hospital, potentially with kidney damage?

Brian Coombes is professor and chair of the Department of Biochemistry and Biomedical Sciences at McMaster University, and the Canada Research Chair in Infectious Disease Pathogenesis. His lab's major focus is onCoombes, a fellow of the American Academy of Microbiology, shares what you need to know about E. coli and how to prevent it.Escherichia coli is a bacteria that is mainly found in the guts of mammals. In most cases, E.

The strains associated with outbreaks tend to have a very low infectious dose and so even a small number of bacteria can spread to many people relatively easily.For the E. coli strains linked to the recent outbreak in Alberta, there are fewthat target the bacteria directly. Antibiotics can not be used because they make the illness worse by making the bacteria produce more of the toxin that is harming the body.

 

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