Acromegaly is a rare disorder caused by a tumor on a person’s pituitary gland that causes the release of too much growth hormone, often enlarging hands and feet and internal organs, which, if left untreated, can be deadly.
Scott Struthers, Crinetics’ founder and CEO, said that it took more than a few tries to discover a molecule capable of doing the job that could also survive the human digestive system. If approved by the U.S. Food and Drug Administration, Paltusotine would be the company’s first drug on the market, a milestone that, according to a statement released by the company, would validate its ability to design and deploy small molecules capable of targeting specific receptors capable of interacting with the endocrine system.
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