However, they say cannabidiol is effective in people with epilepsy, and cannabis-based medicines can help people with multiple sclerosis, chronic pain, inflammatory bowel disease, and in palliative care.
An increasing number of studies have examined the effects of cannabinoids on health and other outcomes, but most findings are observational and prone to bias, making it difficult to draw firm conclusions. The researchers graded the evidence as high, moderate, low, or critically low certainty in randomized trials - and as convincing, highly suggestive, suggestive, weak, or not significant in observational studies, based on quantitative criteria.
Related StoriesBased on weak to suggestive observational evidence and high to moderate certainty trial evidence, the researchers also found an association between cannabis and general psychiatric symptoms, including depression and mania, as well as detrimental effects on memory, verbal and visual recall.
Cannabidiol was, however, beneficial in reducing seizures in certain types of epilepsy, while cannabis-based medicines were beneficial for pain and muscle stiffness in multiple sclerosis, as well as for chronic pain in various conditions, and in palliative care, yet not without adverse events.
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