, has revealed that a common weight-loss surgery for overweight adolescents and young adults may have adverse impacts on bone health.
For the study, participants between the age of 13 and 24 years were enrolled from 2015 to 2020. The adolescents and young adults had moderate to severe obesity. The young adults had a body max index of 35 or above. A BMI of 30 or above is considered obese. Adolescent participants were at 120% of the 95th age- and sex-specific percentile.
Before and 24 months after sleeve gastrectomy, participants underwent a physical examination, blood tests, and quantitative CT of the lumbar spine, to quantify volumetric bone mineral density and to perform finite element analysis, a technique that can estimate bone strength. Quantitative CT is a highly accurate technique for detecting changes in volumetric bone mineral density after extreme weight loss.
“We found that bone strength was lower two years after weight-loss surgery, while bone marrow fat, a marker of bone weakening, was increased, suggesting that weight-loss surgery has negative effects on bone health,” Dr. Bredella said.
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