]. PICS is a neurologically heterogenous syndrome that affects patients weeks to months after discharge from the ICU and manifests with impairments in at least one of the following three domains: physical, cognitive, and psychological health.
This is the first guideline on multimodal rehabilitative therapies for patients affected by PICS based on the critical appraisal of the present scientific evidence. A multidisciplinary task force addressed 10 principal research questions pertaining to the rehabilitative therapy of PICS and searched for the best available evidence, determined its quality, and formulated therapy recommendations. The task force extracted four strong recommendations, eight recommendations and 4 therapy options.
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