Prognostic relevance of gait-related cognitive functions for dementia conversion in amnestic mild cognitive impairment - BMC Geriatrics

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A study in BMCGeriatr finds that amnestic mild cognitive impairment gait abnormalities lead to executive functions/attention deterioration and conversion to Alzheimer’s dementia. This interaction can help design interventions that target both domains.

Ethical approval for data collection and sharing was given by the institutional review boards of the participating institutions in the Alzheimer's Disease Neuroimaging Initiative .

This study will be conducted in accordance with good clinical practice guidelines, the Declaration of Helsinki, US 21CFR Part 50—Protection of Human Subjects and Part 56—Institutional Review Boards, and in compliance with state and federal HIPAA regulations. Written informed consent for the study must be obtained from all subjects and / or authorized representatives and study partners before protocol-specific procedures are performed.

The Ethics committees/institutional review boards that approved the ADNI study are: Albany Medical Center Committee on Research Involving Human Subjects Institutional Review Board, Boston University Medical Campus and Boston Medical Center Institutional Review Board, Butler Hospital Institutional Review Board, Cleveland Clinic Institutional Review Board, Columbia University Medical Center Institutional Review Board, Duke University Health System Institutional Review Board, Emory Institutional...

Board, University of Alabama Office of the IRB, University of British Columbia Research Ethics Board, University of California Davis Institutional Review Board Administration, University of California Los Angeles Office of the Human Research Protection Program, University of California San Diego Human Research Protections Program, University of California San Francisco Human Research Protection Program, University of Iowa Institutional Review Board, University of Kansas Medical Center Human...

 

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