Experimental insulin implant uses electricity to control genes

📆 8/1/2023 6:29 PM
📰 Nature

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Genetically engineered human cells that produce insulin when stimulated by a small electric current could one day be used to develop better treatments for type 1 diabetes

, offer hope that this technology could one day be incorporated into medical implants, says co-author Martin Fussenegger, a bioengineer at the Swiss Federal Institute of Technology in Zurich.

Fussenegger and his colleagues engineered insulin-producing cells that could be activated electrically by manipulating their response to ROS. These toxic molecules are produced naturally during cell metabolism but their formation can also be induced by applying a direct current to the cells.

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