SGLT2 inhibitors can reduce the incidence of abnormal blood glucose caused by statins in non-diabetes patients with HFrEF after PCI - BMC Cardiovascular Disorders

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A study in BMCCardiovascDisord finds that SGLT2 inhibitors play a protective role in reducing the risk of statins-induced abnormal blood glucose levels in non-diabetes patients with heart failure with reduced ejection fraction.

]. The Canadian Cardiovascular Society / Canadian Heart Failure Society Heart Failure Guidelines recommend the use of an SGLT2 inhibitor in patients with HFrEF, with or without concomitant type 2 diabetes, to improve symptoms and quality of life and to reduce the risk of hospitalization due to heart failure and/or cardiovascular mortality [

]. It is still unknown whether SGLT2 inhibitors can reduce the risk of statin-induced abnormal blood glucose in non-diabetes patients with HFrEF after PCI. Thus, this study aimed to explore the possibility.This is a single-center prospective cohor study. A total of 408 patients who underwent PCI at the Affiliated Hospital of Qingdao University between June 2017 and August 2020 are included.

 

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