The results of the 4,000-person study were favorable; the medication lowered LDL cholesterol by roughly 21%.The study ran for just under three years and was comprised of patients with no history of heart disease but were at high risk for cardiovascular events like heart attacks or strokes. Participants were also unable or unwilling to take statins.
This isn’t the first time bempedoic acid has been looked at for its use in lowering cholesterol. Prior to this study, research “Those are things that need to be investigated in more detail but not to a degree enough that would be considered unsafe or unable to use the drug,” she added.muscle soreness and muscle weakness“There are a lot of people who won’t or can’t take statins who still need cholesterol lowering and that’s where these drugs like bempedoic acid come in,” said, a preventive cardiologist at Saint Luke’s Mid America Heart Institute who was not affiliated with the study.
Why are statins the first choice? They’re more effective, O’Keefe stressed. They lower cholesterol anywhere from 40% to 50%, while bempedoic acid lowered cholesterol at 21% in the JAMA study. In other words, bempedoic acid’s “not going to be nearly as strong,” he said.
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