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Fluctuating levels of cholesterol and triglycerides linked to increased risk of dementia

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Older people who have fluctuating levels of cholesterol and triglycerides may have a higher risk of Alzheimer's disease and related dementias compared to people who have steady levels, according to new research published in online issue of Neurology. While the study found a link, it does not prove that fluctuating levels of cholesterol and triglycerides cause dementia.

on at least three different days in the five years before the start of the study.

Then researchers divided participants into five equal groups based on how much the measurements fluctuated. The lowest group had the least variation over time and the highest group had the most variation. Participants were followed for an average of 13 years. During that time, 2,473 people developed Alzheimer's disease or another form of dementia.and lipid-lowering treatments, researchers found for total cholesterol, participants in the highest group had a 19% increased risk of dementia compared to those in the lowest group. Of the 2,311 people in the highest group, 515 developed dementia compared to 483 of the 2,311 people in the lowest group.

A limitation of the study was researchers looked at Alzheimer's disease and related dementias as a whole and did not differentiate between the types of

 

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