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Association of Mediterranean diet with survival after breast cancer diagnosis in women from nine European countries: results from the EPIC cohort study - BMC MedicineBackground The Mediterranean diet has been associated with lower risk of breast cancer (BC) but evidence from prospective studies on the role of Mediterranean diet on BC survival remains sparse and conflicting. We aimed to investigate whether adherence to Mediterranean diet prior to diagnosis is associated with overall and BC-specific mortality. Methods A total of 13,270 incident breast cancer cases were identified from an initial sample of 318,686 women in 9 countries from the European Prospective Investigation into Cancer and Nutrition (EPIC) study. Adherence to Mediterranean diet was estimated through the adapted relative Mediterranean diet (arMED), a 16-point score that includes 8 key components of the Mediterranean diet and excludes alcohol. The degree of adherence to arMED was classified as low (score 0–5), medium (score 6–8), and high (score 9–16). Multivariable Cox proportional hazards models were used to analyze the association between the arMED score and overall mortality, and Fine-Gray competing risks models were applied for BC-specific mortality. Results After a mean follow-up of 8.6 years from diagnosis, 2340 women died, including 1475 from breast cancer. Among all BC survivors, low compared to medium adherence to arMED score was associated with a 13% higher risk of all-cause mortality (HR 1.13, 95%CI 1.01–1.26). High compared to medium adherence to arMED showed a non-statistically significant association (HR 0.94; 95% CI 0.84–1.05). With no statistically significant departures from linearity, on a continuous scale, a 3-unit increase in the arMED score was associated with an 8% reduced risk of overall mortality (HR3-unit 0.92, 95% CI: 0.87–0.97). This result sustained when restricted to postmenopausal women and was stronger among metastatic BC cases (HR3-unit 0.81, 95% CI: 0.72–0.91). Conclusions Consuming a Mediterranean diet before BC diagnosis may improve long-term prognosis, particularly after menopause and in cases of metastatic breast cancer. Well
Source: BioMedCentral - 🏆 22. / 71 Read more »
Diet Coke ingredient to be declared possible cause of cancerThe World Health Organisation is reportedly set to list aspartame, a popular artificial sweetener used in products such as Diet Coke, as a ‘possibly carcinogenic to humans’.
Source: MetroUK - 🏆 13. / 82 Read more »
Diet Coke ingredient to be declared possible cause of cancerThe World Health Organisation is set to declare an artificial sweetener as a possible cause of cancer. If the decision is made, this might just cause a shake-up for major products that we all know today. Read more 👉
Source: MetroUK - 🏆 13. / 82 Read more »
How worried should we be about aspartame? We asked the expertsThe popular Diet Coke ingredient is set to be declared as “possibly carcinogenic” – but what does that mean?
Source: StylistMagazine - 🏆 133. / 51 Read more »
AMLO’s austerity has hurt MexicoThe effect of AMLO’s spending policies is to make Mexico’s economy, and its democracy, weaker than they should be
Source: TheEconomist - 🏆 6. / 92 Read more »
Why you can ignore the WHO claims that aspartame sweetener is a cancer riskThe WHO is about to declare that aspartame (a sweetener used most famously in diet drinks) is a cancer risk This seems surprising, because aspartame has repeatedly been declared safe by multiple health authorities 🖊️ Analysis StuartJRitchie
Source: i newspaper - 🏆 8. / 89 Read more »